METHODS OF MODULATING INFLAMMATION BY ADMINISTRATION OF INTERLEUKIN-19 AND INHIBITORS OF IL-19 BINDING

摘要

Methods for modulating inflammation using IL-19 polypeptides and inhibitors of IL-19 binding to an IL-19 receptor are disclosed. The present invention also provides the human IL-19 promoter and use of the promoter to detect polymorphisms in the II-19 promoter region of an individual. Also disclosed are purified and isolated murine IL-19 polynucleotides and polypeptides.