发明名称 Method for synthesis of silylated ascorbic acid derivatives
摘要 A compound of Formula (I), as defined in the specification, and a method for its synthesis. The method includes providing an inert environment, minimizing exposure of the reaction environment to visible light and reacting ascorbic acid with solvent and a compound of the Formula (II), as defined in the specification. The method of the present invention produces increased yields and a compound having increased stability and the same or greater bioactivity than ascorbic acid. The compound formed by the method of the present invention is capable for use in anhydrous cosmetic, dermatological and pharmaceutical compositions as an active agent for combating aging of the skin and improving its aesthetic appearance.
申请公布号 US2005112158(A1) 申请公布日期 2005.05.26
申请号 US20040972465 申请日期 2004.10.25
申请人 CLARIANT INTERNATINONAL, LTD. 发明人 TERRY W. L.JR.;LEGROW GARY E.;LITTAU CHERYL
分类号 A61K8/55;A61K8/00;A61K8/58;A61K8/67;A61K31/375;A61P17/16;A61Q19/00;A61Q19/08;C07F7/18;(IPC1-7):A61K31/695;C07F7/02 主分类号 A61K8/55
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