СПОСОБ ПРОГНОЗИРОВАНИЯ ПЕРИНАТАЛЬНОЙ ПАТОЛОГИИ У БЕРЕМЕННЫХ С ХРОНИЧЕСКМИ ИНФЕКЦИОННО-ВОСПАЛИТЕЛЬНЫМИ ЗАБОЛЕВАНИЯМИ

摘要

FIELD: medicine, gynecology. ^ SUBSTANCE: in pregnant women one should detect the capacity of blood leukocytes to produce gamma-interferon, detect antibodies to gamma-interferon and autoantibodies to OBM and S-100 proteins. At decreased production of gamma-interferon being below 16 IU/ml, autoantibodies to OBM and S-100 being below (-) 40 c.u. for each parameter and increased value of antibodies to gamma-interferon being above 20 c.u. one should predict perinatal pathology. The method suggested requires no surgical interference to obtain spinal fluid. Modern application of adequate curative-prophylactic measures in pregnant women with predicted perinatal pathology enables to reduce the frequency of severe forms of intrauterine infection from 26.7% to 11.9%; the frequency of perinatal pathology of infectious nature from 25.2% to 13.3%. ^ EFFECT: higher efficiency and accuracy of prediction. ^ 2 ex