发明名称 PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS
摘要 A compound of Formula (I): wherein: A is phenyl or a 5- or 6-membered heteroaryl ring, optionally substituted; R<1> and R<2> are selected from hydrogen and methyl; with the proviso that at least one of R<1> and R<2> is methyl; or a salt, pro-drug or solvate thereof, are described. Their use as GLK activators, pharmaceutical compositions containing them, and processes for their preparation are also described.
申请公布号 WO2005044801(A1) 申请公布日期 2005.05.19
申请号 WO2004GB04579 申请日期 2004.10.28
申请人 ASTRAZENECA AB;ASTRAZENECA UK LIMITED;CAULKETT, PETER, WILLIAM, RODNEY;JOHNSTONE, CRAIG;MCKERRECHER, DARREN;PIKE, KURT, GORDON 发明人 CAULKETT, PETER, WILLIAM, RODNEY;JOHNSTONE, CRAIG;MCKERRECHER, DARREN;PIKE, KURT, GORDON
分类号 A61K31/44;A61K31/443;A61P3/10;C07D213/80;C07D405/12;C07D409/12;(IPC1-7):C07D213/80 主分类号 A61K31/44
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