DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH ORGANIC CATIONIC TRANSPORTER-LIKE 3 (ORCTL3) (ORCTL3)

摘要

The invention provides a human ORCTL3 which is associated with the cardiovascular diseases, gastroenterological diseases, cancer, inflammation, metabolic diseases, neurological diseases and urological diseases,. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, gastroenterological diseases, cancer, inflammation, metabolic diseases, neurological diseases and urological diseases,. The invention also features compounds which bind to and/or activate or inhibit the activity of ORCTL3 as well as pharmaceutical compositions comprising such compounds.