发明名称 |
Inhibitors of cyclin-dependent kinases, compositions and uses related thereto |
摘要 |
The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation.
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申请公布号 |
US2005090471(A1) |
申请公布日期 |
2005.04.28 |
申请号 |
US20040492116 |
申请日期 |
2004.10.04 |
申请人 |
GPC BIOTECH AG |
发明人 |
BOCKOVICH NICHOLAS;KLUGE ARTHUR;RAM SIYA;WANG ZHONGGUO;OALMANN CHRIS;MURTHI KRISHNA K.;BECKER FRANK |
分类号 |
A61K31/496;A61K31/522;A61K31/5377;A61K31/675;A61P17/14;A61P31/12;A61P31/18;A61P35/00;A61P43/00;C07D231/54;C07D403/12;C07D487/04;C07F9/6558;C07F9/6561;C40B30/04;G01N33/68;(IPC1-7):A61K31/675;A61K31/519;C07D487/02 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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