<p>Disclosed is a pyrimidine derivative with excellent MLR inhibitory effect or a pharmacologically acceptable salt thereof. Specifically, disclosed is a pyrimidine derivative represented by the general formula (I) below or a pharmacologically acceptable salt thereof. (I) (In the formula, R<1> represents a lower alkyl group; R<2> represents an aryl group or the like; A represents -NH- or the like; R<3> represents -NHR<6> group (wherein R<6> represents an aryl group or the like) or the like; R<4> represents a hydrogen atom or the like; and R<5> represents a heterocyclic group or the like.)</p>
