发明名称 |
CELL SURFACE MOLECULES AS MARKERS AND THERAPEUTIC AGENTS AGAINST KIDNEY CANCERS |
摘要 |
<p>Human cell surface molecules CD70 and CD203C are expressed at higher levels in kidney carcinomas, particularly renal cell carcinomas and clear cell renal cell carcinomas, yet are expressed at low levels in normal kidney and other diseased kidney tissue, and at low levels in other tissues. CD70 and CD203c show specified towards kidney carcinomas, particularly renal cell carcinomas and clear cell renal cell carcinomas and thus can be used as diagnostic markers and therapeutic targets for these diseases. In addition, antibodies or small molecules against these molecules could be used in treatments towards these diseases.</p> |
申请公布号 |
WO2005036176(A1) |
申请公布日期 |
2005.04.21 |
申请号 |
WO2004US23795 |
申请日期 |
2004.07.26 |
申请人 |
WYETH;LIU, WEI;WHITLEY, MARYANN;SLONIM, DONNA;HOWES, STEVEN |
发明人 |
LIU, WEI;WHITLEY, MARYANN;SLONIM, DONNA;HOWES, STEVEN |
分类号 |
A61K47/48;G01N33/574;(IPC1-7):G01N33/574;A61K39/395 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|