发明名称 |
NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE |
摘要 |
The invention concerns compounds selected from the set consisting of (i) compounds of formula (I) in which: X represents a halogen atom or a methyl group; A represents a -N(R3)-CO or -CO-N(R3)- group; B represents- a single bond, -CH2- or -CH2-O-; R1 represents H, a C1-C3 alkyl group, or a CF3 group; R2 and R3 each represent independently H or a C1-C3 alkyl group; W represents CH or N; n represents 2, 3, 4 or 5; and (ii) the additive salts. The invention also concerns their method of preparation and their therapeutic use, particularly with regard to pathologies involving bradykinine.
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申请公布号 |
CA2273894(C) |
申请公布日期 |
2005.04.19 |
申请号 |
CA19972273894 |
申请日期 |
1997.11.14 |
申请人 |
FOURNIER INDUSTRIE ET SANTE |
发明人 |
BONDOUX, MICHEL;DODEY, PIERRE;BARTH, MARTINE;OU, KHAN;HOUZIAUX, PATRICK |
分类号 |
A61P25/04;A61K31/4709;A61P11/06;A61P27/16;A61P29/00;A61P43/00;C07D401/12;C07D401/14;(IPC1-7):C07D401/12;A61K31/47 |
主分类号 |
A61P25/04 |
代理机构 |
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主权项 |
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地址 |
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