发明名称 NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE
摘要 The invention concerns compounds selected from the set consisting of (i) compounds of formula (I) in which: X represents a halogen atom or a methyl group; A represents a -N(R3)-CO or -CO-N(R3)- group; B represents- a single bond, -CH2- or -CH2-O-; R1 represents H, a C1-C3 alkyl group, or a CF3 group; R2 and R3 each represent independently H or a C1-C3 alkyl group; W represents CH or N; n represents 2, 3, 4 or 5; and (ii) the additive salts. The invention also concerns their method of preparation and their therapeutic use, particularly with regard to pathologies involving bradykinine.
申请公布号 CA2273894(C) 申请公布日期 2005.04.19
申请号 CA19972273894 申请日期 1997.11.14
申请人 FOURNIER INDUSTRIE ET SANTE 发明人 BONDOUX, MICHEL;DODEY, PIERRE;BARTH, MARTINE;OU, KHAN;HOUZIAUX, PATRICK
分类号 A61P25/04;A61K31/4709;A61P11/06;A61P27/16;A61P29/00;A61P43/00;C07D401/12;C07D401/14;(IPC1-7):C07D401/12;A61K31/47 主分类号 A61P25/04
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