MODULATION VON OLIGONUKLEOTID CPG-VERMITTELTER IMMUNSTIMULATION DURCH MODIFIKATION DER NUCLEOSIDE

摘要

The invention provides methods for modulating the immune response caused by CpG dinucleotide-containing compounds. The methods according to the invention enables both decreasing the immunostimulatory effect for antisense applications, as well as increasing the immunostimulatory effect for immunotherapy applications.