DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH ORGANIC CATION TRANSPORTER SLC22A12 (SLC22A12)

摘要

The invention provides a human SLC22A12 which is associated with the cardiovascular diseases, reproduction diseases, urological diseases and cancer. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, reproduction diseases, urological diseases and cancer. The invention also features compounds which bind to and/or activate or inhibit the activity of SLC22A12 as well as pharmaceutical compositions comprising such compounds.