发明名称 |
Inhibition of differentiation of cytotoxic T-cells by P-selectin ligand (PSGL) antagonists |
摘要 |
Use of a mimetic which inhibit sLex binding in the manufacture of a medicament for treating ameliorating an autoimmune condition and/or ameliorating an allergic reaction is disclosed, wherein differentiation of an activated T-cell into a cytotoxic lymphocyte in a mammalian subject is inhibited. (62) Divided Out of 511836
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申请公布号 |
NZ528610(A) |
申请公布日期 |
2005.03.24 |
申请号 |
NZ19990528610 |
申请日期 |
1999.10.29 |
申请人 |
GENETICS INSTITUTE, LLC;CBR LABORATORIES, INC |
发明人 |
MANJUNATH, NARASIMHASWAMY;HANS VON ANDRIAN, ULRICH |
分类号 |
C12N5/06;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61P31/12;A61P35/00;A61P37/00;A61P37/08;C07K16/28;(IPC1-7):A61K38/16 |
主分类号 |
C12N5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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