MPTENS AS MODIFIERS OF THE PTEN/IGF PATHWAY AND METHODS OF USE
摘要
Human MPTEN genes are identified as modulators of the PTEN/IGF pathway, and thus are therapeutic targets for disorders associated with defective PTEN/IGF function. Methods for identifying modulators of PTEN/IGF, comprising screening for agents that modulate the activity of MPTEN are provided.
申请公布号
WO2005003297(A3)
申请公布日期
2005.03.24
申请号
WO2004US14966
申请日期
2004.05.13
申请人
EXELIXIS, INC.;SONG, CHUNYAN;OLLMANN, MICHAEL, MARTIN;LICKTEIG, KIM;ZHANG, HAIGUANG;BJERKE, LYNN, MARGARET
发明人
SONG, CHUNYAN;OLLMANN, MICHAEL, MARTIN;LICKTEIG, KIM;ZHANG, HAIGUANG;BJERKE, LYNN, MARGARET