发明名称 MPTENS AS MODIFIERS OF THE PTEN/IGF PATHWAY AND METHODS OF USE
摘要 Human MPTEN genes are identified as modulators of the PTEN/IGF pathway, and thus are therapeutic targets for disorders associated with defective PTEN/IGF function. Methods for identifying modulators of PTEN/IGF, comprising screening for agents that modulate the activity of MPTEN are provided.
申请公布号 WO2005003297(A3) 申请公布日期 2005.03.24
申请号 WO2004US14966 申请日期 2004.05.13
申请人 EXELIXIS, INC.;SONG, CHUNYAN;OLLMANN, MICHAEL, MARTIN;LICKTEIG, KIM;ZHANG, HAIGUANG;BJERKE, LYNN, MARGARET 发明人 SONG, CHUNYAN;OLLMANN, MICHAEL, MARTIN;LICKTEIG, KIM;ZHANG, HAIGUANG;BJERKE, LYNN, MARGARET
分类号 C07K14/47;C12N;C12N5/00;C12Q1/42;C12Q1/68;G01N33/50;G01N33/53;G01N33/566;G01N33/74 主分类号 C07K14/47
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