| 摘要 |
FIELD: medicine, oncology, pharmacy. ^ SUBSTANCE: invention describes a liquid pharmaceutical composition used in treatment of cancer and comprising vinorelbin as an active component and is useful for incapsulation into soft capsules. The liquid oral pharmaceutical composition useful as a liquid filling agent composition for the dosed formulation as a soft capsule comprises vinorelbin or its pharmaceutically acceptable salt, in particular, vinorelbin tartrate, ethanol, water, glycerol and polyethylene glycol. Also, invention relates to a method for preparing cancer that involves oral administration to a patient a soft capsule comprising the pharmaceutical composition. The liquid composition containing vinorelbin proves the improved solubility and bioavailability for oral administration. ^ EFFECT: improved and valuable pharmaceutical and medicinal properties of pharmaceutical composition. ^ 13 cl, 7 tbl, 6 ex |
