发明名称 NOVEL UBP8RP POLYPEPTIDES AND THEIR USE IN THE TREATMENT OF PSORIASIS
摘要 The invention encompasses a novel gene encoding a protein of the ubiquitin- proteasome pathway, UBP8rp. The invention also relates the use of UBP8rp polypeptides for screening for modulators, and to the use of said modulators for treating chronic inflammatory diseases such as, e.g., psoriasis, psoriat ic arthritis, rheumatoid arthritis, asthma, inflammatory bowel disease and multiple sclerosis. The invention further relates to the use of biallelic markers located in the UBP8rp gene for diagnosing said chronic inflammatory diseases.
申请公布号 CA2536793(A1) 申请公布日期 2005.03.17
申请号 CA20042536793 申请日期 2004.09.02
申请人 APPLIED RESEARCH SYSTEMS ARS HOLDING N.V 发明人 GUERASSIMENKO, OXANA;CHUMAKOV, ILYA
分类号 C12N9/16;C07K14/47;C12N15/00;C12Q1/68 主分类号 C12N9/16
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