发明名称 |
SOMATOSTATIN ANALOG DERIVATIVE AND USE THEREOF |
摘要 |
PROBLEM TO BE SOLVED: To obtain a medicine composition for treatment and diagnosis that has low kidney accumulation, is safe, has high precision and is obtained by using a metal. SOLUTION: The carrier substance represented by formula (I) (R is a chelator residue; X is a phenyl group or a naphthyl group containing one or more free carboxy groups or amino groups; Y is a group selected from Thr-OH, Thr-NH<SB>2</SB>and Trp-NH<SB>2</SB>; A is Phe or Tyr; B is Thr or Val) is used for delivering a metal for diagnosis and/or treatment to a target cell expressing a somatostatin-bonding receptor. COPYRIGHT: (C)2005,JPO&NCIPI
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申请公布号 |
JP2005068046(A) |
申请公布日期 |
2005.03.17 |
申请号 |
JP20030297606 |
申请日期 |
2003.08.21 |
申请人 |
NIHON MEDI PHYSICS CO LTD |
发明人 |
SAITO HIROSHI;SAJI HIDEO;ARANO YASUSHI;IWATO AKIMASA;MIFUNE MASAKI;MUKAI TAKAHIRO;AKISAWA HIROYUKI;TAKIMOTO YAMATO |
分类号 |
A61K47/42;A61K38/04;A61K51/00;A61P35/00;C07K7/54;(IPC1-7):A61K38/04 |
主分类号 |
A61K47/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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