发明名称 |
Synthesis of epothilones, intermediates thereto and analogues thereof |
摘要 |
The present invention provides convergent processes for preparing epothilones, desoxyepothilones, and analogues thereof. The present invention further provides novel compositions and methods for the treatment of cancer and additionally provides methods for the treatment of cancer which has developed a multi-drug phenotype. |
申请公布号 |
US6867305(B2) |
申请公布日期 |
2005.03.15 |
申请号 |
US20010796959 |
申请日期 |
2001.03.01 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
DANISHEFSKY SAMUEL J.;STACHEL SHAWN J.;LEE CHUL BOM;CHAPPELL MARK D.;WU ZHICAL |
分类号 |
A61K31/337;A61K31/475;A61K45/06;C07D277/30;C07D417/06;(IPC1-7):C07D263/32 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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