METHOD OF CONSTRUCTING TRANSGENIC BIRD USING LENTIVIRUS VECTOR AND TRANSGENIC BIRD OBTAINED THEREBY

摘要

It is intended to provide a lentivirus vector containing VSV-G in the coat protein; a recombinant bird host obtained by infecting a bird host with the lentivirus vector and a method of constructing the same; and a transgenic chimeric bird constructed by the infection with the lentivirus vector and its offspring. It is also intended to provide a method of constructing a G0 transgenic chimeric bird and its offspring which comprises infecting an early embryo in a fertilized bird egg with a lentivirus vector containing VSV-G in the coat protein and then hatching the embryo; and a G0 transgenic chimeric bird and its offspring constructed by the above method. Namely, a transgenic bird which is constructed by infecting an early bird embryo with a lentivirus vector having VSV-G in its coat protein.