| 摘要 |
FIELD: organic synthesis. ^ SUBSTANCE: 1-(2-pyridyl)-1,2-ethandiol finding use as starting compound in synthesis of therapeutical preparations (ethoxadrol, dexoxadrol, laevoxadrol, and dioxadrol) and as a component in synthesis of polyester polymers is prepared via interaction of equimolar amounts of 2-vinylpyridine and 5% potassium permanganate aqueous solution in water/acetone mixture (3:2 by volume) followed by neutralization of reaction mixture with sulfuric acid in presence of isopropyl alcohol and isolation of desired product. ^ EFFECT: increased yield and purity of product. |
