发明名称 SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS
摘要 This invention provides azoles which may be useful as inhibitors of protein tyrosine phosphatases (PTPases). The present invention provides compounds of Formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds and their use in treating human or animal disorders. The compounds of the invention may be useful as inhibitors of protein tyrosine phosphatases and thus can be useful for the management, treatment, control and adjunct treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes, Type II diabetes.
申请公布号 WO2004071447(B1) 申请公布日期 2005.03.10
申请号 WO2004US04074 申请日期 2004.02.12
申请人 TRANSTECH PHARMA INC.;MJALLI, ADNAN, M.M.;ANDREWS, ROBERT, C.;YARRAGUNTA, RAVINDRA, R.;XIE, RONGYUAN;SUBRAMANIAN, GOVINDAN;QUADA, JR., JAMES, C.;ARIMILLI, MURTY, N.;POLISETTI, DHARMA, R. 发明人 MJALLI, ADNAN, M.M.;ANDREWS, ROBERT, C.;YARRAGUNTA, RAVINDRA, R.;XIE, RONGYUAN;SUBRAMANIAN, GOVINDAN;QUADA, JR., JAMES, C.;ARIMILLI, MURTY, N.;POLISETTI, DHARMA, R.
分类号 A61K;A61K31/40;A61K31/4178;A61K31/422;A61K31/426;C07D233/54;C07D263/32;C07D401/10;C07D401/12;C07D403/04;C07D403/10;C07D403/12;C07D405/10;C07D405/12;C07D407/12;C07D413/04;C07D417/12;(IPC1-7):C07D233/54 主分类号 A61K
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