发明名称 Indazole derivatives as JNK inhibitors.
摘要 Compounds having activity as selective inhibitors of JNK are disclosed. The compounds of this invention are indazole derivatives having the following structure: wherein R<SUB>1</SUB>, R<SUB>2 </SUB>and A are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to JNK inhibition. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
申请公布号 ZA200300886(B) 申请公布日期 2005.03.09
申请号 ZA20030000886 申请日期 2003.01.31
申请人 SIGNAL PHARMACEUTICALS, INC. 发明人 SHRIPAD S BHAGWAT;YOSHITAKA SATOH;STEVEN T. SAKATA
分类号 A61K31/41;A61K31/416;A61K31/4178;A61K31/4184;A61K31/4196;A61K31/42;A61K31/4245;A61K31/427;A61K31/4409;A61K31/4439;A61K31/4453;A61K31/454;A61K31/4709;A61K31/496;A61K31/506;A61K31/5377;A61K31/55;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P11/08;A61P13/12;A61P17/02;A61P17/08;A61P19/02;A61P19/06;A61P19/08;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P27/08;A61P27/16;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/02;A61P37/06;C07D231/56;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/12;C07D403/14;C07D405/04;C07D405/12;C07D405/14;C07D409/04;C07D409/12;C07D409/14;C07D413/04;C07D413/14;C07D417/12 主分类号 A61K31/41
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