| 发明名称 |
METHOD OF MANUFACTURING OF 7-ETHYL-10-[4-(1-PIPERIDINO)-1- PIPERIDINO]- CARBONYLOXYCAMPTOTHECIN |
| 摘要 |
<p>The invention relates to the method of manufacturing of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin by condensation of 7-ethyl-l0-hydroxycamptothecin with 1-chlorocarbonyl-4-piperidinopiperidine hydrochloride in a polar aprotic solvent in the presence of 4-dimethylaminopyridine.</p> |
| 申请公布号 |
WO2005019223(A1) |
申请公布日期 |
2005.03.03 |
| 申请号 |
WO2004CZ00050 |
申请日期 |
2004.08.24 |
| 申请人 |
PLIVA-LACHEMA A.S.;DOBROVOLNY, PETR |
发明人 |
DOBROVOLNY, PETR |
| 分类号 |
C07D491/22;(IPC1-7):C07D491/22 |
主分类号 |
C07D491/22 |
| 代理机构 |
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