发明名称 |
Process for producing optically active amide from alpha beta- unsaturated amide derivative in the presence of transition metal complex containing phosphine-phosphorane compound and transition metal |
摘要 |
A novel process for producing an optically active amide excellent in chemical selectivity and enantioselectivity by asymmetric hydrogenation of an alpha,beta-unsaturated amide and also allowing the reaction to proceed efficiently even when a trace amount of a catalyst is used relative to the substrate as compared with the amount in a conventional process. An optically active amide is produced by asymmetric hydrogenation of an alpha,beta-unsaturated amide derivative in the presence of a transition metal complex containing a specific phosphine-phosphorane compound.
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申请公布号 |
US6855847(B2) |
申请公布日期 |
2005.02.15 |
申请号 |
US20020198930 |
申请日期 |
2002.07.22 |
申请人 |
TAKASAGO INTERNATIONAL CORPORATION |
发明人 |
MATSUMURA KAZUHIKO;SAITO TAKAO |
分类号 |
B01J31/24;C07B61/00;C07C231/12;C07C231/18;C07C233/05;C07C233/47;C07C233/65;C07F9/50;C07F9/6568;C07F15/00;C07F19/00;(IPC1-7):C07C233/05 |
主分类号 |
B01J31/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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