摘要 |
<P>PROBLEM TO BE SOLVED: To provide a technique for inhibiting transcription of a gene, capable of being applied to a wider range in a simpler manner than ever, in a method for inhibiting the transcription of the gene, and to provide a method for utilizing the same. <P>SOLUTION: A peptide provided in the specification has an amino acid sequence expressed by: α<SP>1</SP>-Leu-β<SP>1</SP>-Leu-γ<SP>1</SP>-Leu (α<SP>1</SP>is Asp, Asn, Glu, Gln, Thr or Ser; β<SP>1</SP>is Asp, Gln, Asn, Arg, Glu, Thr, Ser or His; and γ<SP>1</SP>is Arg, Gln, Asn, Thr, Ser, His, Lys or Asp), an amino acid sequence of sequence number 63, or an amino acid sequence of sequence number 66. Because the peptide is extremely short in size, the peptide is easily synthesized and effectively inhibits the transcription in which a specified gene is targeted. <P>COPYRIGHT: (C)2005,JPO&NCIPI |