发明名称 |
MODIFICATION OF CYCLOOXYGENASE AND LIPOXYGENASE ACTIVITY WITH ASTERIDAE EXTRACTS AND OPTIONALLY BOSWELLIC ACID |
摘要 |
Extracts from plants in the Asteridae subfamily, such as Carthamus tinctorious, are effective to selectively inhibit COX-2 activity and/or enhance COX-1 activity. When Asteridae extracts are combined with boswellic acid, the combination exhibits a synergistic inhibitory effect on both COX-2 and LO. Such extracts and combinations are used in methods of selectively inhibiting COX-2, inhibiting LO, and/or enhancing COX-1 activity as well as in the methods of treating conditions that would respond favorably to any of these effects.
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申请公布号 |
WO2004052299(B1) |
申请公布日期 |
2005.02.03 |
申请号 |
WO2003US39183 |
申请日期 |
2003.12.09 |
申请人 |
SHAKLEE CORPORATION;ZHANG, PETER, X.;YATCILLA, MICHAEL, T. |
发明人 |
ZHANG, PETER, X.;YATCILLA, MICHAEL, T. |
分类号 |
A61K;A61K31/19;A61K36/00;A61K36/24;A61K36/28;A61K36/286;A61K36/32;A61K36/324;A61K36/328;A61K36/634;(IPC1-7):A61K35/78 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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