The present invention relates to pharmacodynamic markers for CDKIs including the candidate 2,6,9-tri-substituted purine known as roscovitine. The identity of these markers facilitates the convenient identification of roscovitine-like activity both in vitro and in vivo.
申请公布号
WO2004087954(A3)
申请公布日期
2005.01.27
申请号
WO2004GB01334
申请日期
2004.03.26
申请人
CYCLACEL LIMITED;GREEN, SIMON, R.;FRAME, SHEELAGH;BLAKE, DAVID