发明名称 |
TREATMENT MODELS AND USES THEREOF |
摘要 |
<p>The generation and use of disease models in fish such as zebrafish are provided, in particular use in a screen to identify a gene or test substance that affects a disease state associated with pain or nociception, or pain or nociception. In particular, fish models are used in a screen to identify a gene or test substance that affects activity or effect of a second gene provided transgenically that affects a pain or nociception state of the fish, or a treatment of the fish that affects a pain or nociception state of the fish. A pain state or nociception of model fish is compared with that of mutated or treated fish, allowing for identification of genes and test substances with therapeutic application.</p> |
申请公布号 |
WO2005004591(A1) |
申请公布日期 |
2005.01.20 |
申请号 |
WO2004GB02922 |
申请日期 |
2004.07.07 |
申请人 |
DANIOLABS LIMITED;BARRETT, RUTH;GOLDSMITH, PAUL;FLEMING, ANGELEEN |
发明人 |
BARRETT, RUTH;GOLDSMITH, PAUL;FLEMING, ANGELEEN |
分类号 |
A01K67/027;G01N33/50;(IPC1-7):A01K67/027 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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