发明名称 THE USE OF C-RAF INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
摘要 C-Raf inhibitors, especially oxindole derivatives such as 5-lodo-3-[(3,5­dibromo-4-hydroxyphenyl) methylene]-2-indolinone, are used for the prevention or inhibition of neuronal cell death in a mammal suffering from or susceptible to neurodegenerative disease, cerebral ischaemia, traumatic neuronal injury, epilepsy-associated neuronal loss, paralysis, or spinal cord injury. C-Raf inhibitors are included in the manufacture of compositions for the treatment of neurodegenerative disease, cerebral ischaemia, traumatic neuronal injury, epilepsy-associated neuronal loss, paralysis, or spinal cord injury.
申请公布号 WO2004064733(A3) 申请公布日期 2004.12.29
申请号 WO2004US00011 申请日期 2004.01.13
申请人 UNIV TEXAS 发明人 D MELLO SANTOSH R;CHIN PAUL C
分类号 A61K;A61K31/00;A61K31/40 主分类号 A61K
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