发明名称 |
USE OF BCMA AS AN IMMUNOREGULATORY AGENT |
摘要 |
The disclosure relates to B-cell maturation antigen (BCMA), a receptor for APRIL and BAFF, and its use as an immunoregulatory agent in treatment of immunological disorders such as multiple sclerosis. The disclosure provides methods and compositions for treating neurodegenerative immunological disorders in mammals by administering soluble BCMA, an antibody against BCMA, or an antibody against a BCMA ligand, e.g., APRIL or BAFF. |
申请公布号 |
WO03072713(A3) |
申请公布日期 |
2004.12.23 |
申请号 |
WO2003US05147 |
申请日期 |
2003.02.21 |
申请人 |
BIOGEN IDEC MA INC.;KALLED, SUSAN, L.;REID, HUGH |
发明人 |
KALLED, SUSAN, L.;REID, HUGH |
分类号 |
A61K38/00;C07K14/705 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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