TRANSPORTER SELECTIVELY TRANSPORTING SULFATE CONJUGATE AND ITS GENE

摘要

It is intended to provide a liver-specific organic anion transporter which transports selectively a sulfate conjugate and its gene. A protein capable of selectively transporting a sulfate conjugate; a gene encoding the same, more specifically, a gene having the amino acid sequence represented by SEQ ID NO:1 in Sequence Listing or the base sequence represented by SEQ ID NO:2; and a method of modifying drug dynamics by altering the ability of a protein to selectively transport a sulfate conjugate with the use of the protein participating in the transport of a sulfate conjugate in the liver, an antibody specific thereto and a substance promoting or inhibiting its function.