发明名称 Chemical compounds
摘要 The use of a 3-substituted indole compound of formula (I) or a pharmaceutically acceptable salt, amide or ester thereof; X is CH2 or SO2 and R<1>, R<2>, R<3>, R<4>, R<5>, R<6 >and R<7 >are certain specified organic moieties, for use in the preparation of a medicament for the inhibition of monocyte chemoattractant protein-1 and/or RANTES induced chemotaxis. Pharmaceutical compositions containing certain compounds of formula (I) and novel compounds of formula (I) are also described and claimed.
申请公布号 US6833387(B1) 申请公布日期 2004.12.21
申请号 US20010889516 申请日期 2001.10.02
申请人 ASTRAZENECA AB 发明人 FAULL ALAN W.;KETTLE JASON
分类号 C07D401/12;A61K31/404;A61K31/41;A61K31/4155;A61K31/4178;A61K31/4184;A61K31/42;A61K31/421;A61K31/422;A61K31/423;A61K31/427;A61K31/4439;A61K31/445;A61K31/454;A61K31/496;A61K31/506;A61K31/513;A61K31/5377;A61K31/541;A61K31/635;A61P29/00;C07D209/42;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;(IPC1-7):A61K31/38;C07D209/36 主分类号 C07D401/12
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