发明名称 |
Methods for the identification of inhibitors of ferredoxin NADP oxidoreductase expression or activity in plants |
摘要 |
The present inventors have discovered that ferredoxin NADP oxidoreductase (FNR) is essential for plant growth. Specifically, the inhibition of FNR gene expression in plant seedlings resulted in seedlings that looked pale and very stunted. Thus, FNR can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit FNR expression or activity, comprising: contacting a compound with a FNR and detecting the presence and/or absence of binding between the compound and the FNR, or detecting a decrease in FNR expression or activity. The methods of the invention are useful for the identification of herbicides.
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申请公布号 |
US2004248228(A1) |
申请公布日期 |
2004.12.09 |
申请号 |
US20040770755 |
申请日期 |
2004.02.03 |
申请人 |
ZAYED ADEL;ASCENZI ROBERT;BOYES DOUGLAS;MULPURI RAO;HOFFMAN NEIL;KJEMTRUP SUSANNE;DAVIS KEITH;HAMILTON CAROL;WOESSNER JEFFREY;GORLACH JORN;PHILLIPS KENNETH;SEVALA VEERESH |
发明人 |
ZAYED ADEL;ASCENZI ROBERT;BOYES DOUGLAS;MULPURI RAO;HOFFMAN NEIL;KJEMTRUP SUSANNE;DAVIS KEITH;HAMILTON CAROL;WOESSNER JEFFREY;GORLACH JORN;PHILLIPS KENNETH;SEVALA VEERESH |
分类号 |
C12Q1/26;C12Q1/48;(IPC1-7):C12Q1/48 |
主分类号 |
C12Q1/26 |
代理机构 |
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地址 |
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