发明名称 Novel 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity
摘要 The present invention relates to a group of novel 4,5-dihydro-1H-pyrazo, derivatives which are potent cannabinoid (CB1) receptor antagonists with utility for the treatment of diseases connected with disorders of the cannabinoid system. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification. The invention also relates to methods for the preparation of these compounds, and to pharmaceutical compositions containing one or more of these compounds as an active component.
申请公布号 US2004248944(A1) 申请公布日期 2004.12.09
申请号 US20040490291 申请日期 2004.03.22
申请人 KRUSE CORNELIS G;LANGE JOSEPHUS H. M.;TIPKER JACOBUS;HERREMANS ARNOLDUS H.J.;VAN STUIVENBERG HERMAN H. 发明人 KRUSE CORNELIS G;LANGE JOSEPHUS H. M.;TIPKER JACOBUS;HERREMANS ARNOLDUS H.J.;VAN STUIVENBERG HERMAN H.
分类号 A61K31/415;A61K31/4155;A61K31/454;A61K31/4725;A61K31/496;A61K31/5377;A61K31/541;A61K31/55;A61P1/04;A61P1/08;A61P1/12;A61P3/04;A61P3/10;A61P9/00;A61P11/00;A61P11/06;A61P25/02;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P27/06;A61P31/04;A61P31/12;A61P35/00;A61P39/02;C07D231/06;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D409/04;(IPC1-7):C0749/14;C0743/04;A61K31/443;A61K31/416 主分类号 A61K31/415
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