发明名称 Fluorescent vasoactive intestinal peptide (VIP)
摘要 Light emitting compounds of the formula:wherein R1 is a light-emitting moiety and R2 is a VIP-based peptide, fragment, derivative or analog thereof, said peptide being linked at an amino acid position to (C-X), wherein (C-X) is selected from the group consisting of C=O, C=S, CH(OH), C=C=O, C=NH, CH2, CH(OR), CH(NR), CH(R), CR3R4, and C(OR3)OR4 where R, R3, and R4 are alkyl moieties or substituted alkyl moieties, wherein said compound exhibits substantial biological activity in the presence of a receptor having affinity for VIP-based peptides.
申请公布号 US6821952(B1) 申请公布日期 2004.11.23
申请号 US19990285422 申请日期 1999.04.02
申请人 PERKINELMER LAS, INC. 发明人 DESJARDINS CLARISSA;SLON-USAKIEVICZ JACEK;BEAUDET ALAIN
分类号 C07K7/06;C07K7/14;C07K14/575;G01N33/50;G01N33/569;(IPC1-7):A61K38/00 主分类号 C07K7/06
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