发明名称 |
Glutaminyl based DP IV-inhibitors |
摘要 |
The present invention relates dipeptidyl peptidase IV inhibition and, more particularly, relates to glutaminyl derivatives, wherein the glutamin residue is bound in a peptide manner to a moiety which imitates the amino acid residue prolin, especially to a nitrogen containing moiety, pharmaceutical compositions containing said compounds, and the use of said compounds in inhibiting dipeptidyl peptidase IV and dipeptidyl peptidase IV-like enzyme activity.
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申请公布号 |
US2004229848(A1) |
申请公布日期 |
2004.11.18 |
申请号 |
US20040839122 |
申请日期 |
2004.05.05 |
申请人 |
DEMUTH HANS-ULRICH;HOFFMANN MATTHIAS;HOFFMANN TORSTEN;NIESTROJ ANDRE J;SCHILLING STEPHAN;HEISER ULRICH |
发明人 |
DEMUTH HANS-ULRICH;HOFFMANN MATTHIAS;HOFFMANN TORSTEN;NIESTROJ ANDRE J;SCHILLING STEPHAN;HEISER ULRICH |
分类号 |
A61K31/00;A61K31/4178;A61K31/4184;A61K31/4188;A61K31/4192;C07D205/04;C07D207/08;C07D207/10;C07D207/12;C07D207/16;C07D207/20;C07D207/22;C07D207/24;C07D231/04;C07D231/06;C07D233/02;C07D233/06;C07D233/28;C07D233/42;C07D233/54;C07D249/04;C07D249/08;C07D249/10;C07D257/04;C07D261/04;C07D263/04;C07D263/06;C07D277/04;C07D277/06;C07D295/185;C07D403/04;C07D413/04;C07D417/04;C07D471/04;C07D487/04;C07F9/572;C07F9/59;C07F9/6506;C07F9/6561;(IPC1-7):C07F9/22;A61K31/69;A61K31/66 |
主分类号 |
A61K31/00 |
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