发明名称 |
FREEZE-DRIED MICROPARTICLE PREPARATION AND METHOD FOR PRODUCING THE SAME |
摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a freeze-dried microparticle preparation capable of readily obtaining a microparticle suspension in which very fine particles in which a slightly water-soluble medicine is coated with a lipid mixture are dispersed without causing coagulation when rehydrated, and to provide a method for preparing the preparation. <P>SOLUTION: The present invention provides the freeze-dried microparticle preparation of the slightly water-soluble medicine coated with the lipid mixture containing a lipid and an ionic compound and comprising at least one kind of sugar selected from the group consisting of sucrose, trehalose and xylitol and reproducing the particle diameter of the preparation before lyophilization when rehydrated and provides a method for preparing the preparation. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p> |
申请公布号 |
JP2004323444(A) |
申请公布日期 |
2004.11.18 |
申请号 |
JP20030122392 |
申请日期 |
2003.04.25 |
申请人 |
HAMAMATSU KAGAKU GIJUTSU KENKYU SHINKOKAI |
发明人 |
SONOBE TAKASHI;NOZAWA YASUO;KAMIYA SEITARO |
分类号 |
A61J3/02;A61K9/19;A61K45/00;A61K47/10;A61K47/26;A61K47/44;(IPC1-7):A61K9/19 |
主分类号 |
A61J3/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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