发明名称 INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE
摘要 <p>The present invention relates to compounds of formula (I) or a pharmaceutically acceptable salt, or mixtures thereof, that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are useful as antiviral agents. The invention further relates to pharmaceutically acceptable compositions comprising said compounds either for ex vivo use or for administration to a patient suffering from HCV infection and processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a pharmaceutical composition comprising a compound of this invention.</p>
申请公布号 WO2004092162(A1) 申请公布日期 2004.10.28
申请号 WO2004US11012 申请日期 2004.04.09
申请人 VERTEX PHARMACEUTICALS, INCORPORATED;FARMER, LUC, J.;PERNI, ROBERT, P.;BHISETTI, GOVINDA, RAO;WILSON, KEITH, P. 发明人 FARMER, LUC, J.;PERNI, ROBERT, P.;BHISETTI, GOVINDA, RAO;WILSON, KEITH, P.
分类号 A61K31/401;A61K31/407;A61K31/4155;A61K31/425;A61K31/4745;A61K31/4965;A61K38/04;C07D403/12;C07D417/12;C07D471/02;(IPC1-7):C07D403/12;A61K31/496;A61K31/415 主分类号 A61K31/401
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