发明名称 |
Candida albicans two-component hybrid kinase gene, CaNik1, and use thereof |
摘要 |
A Candida albicans gene, CaNik1, is involved in phenotypic switching which is significant because of a direct correlation between the switching and the level of virulence of the organism. A method of screening for anti-fungal pharmaceutical candidates entails bringing a test substance into contact with cells containing a CaNik1 gene or a variant thereof and then monitoring the effect, if any, on the level of expression of the gene.
|
申请公布号 |
US6803191(B2) |
申请公布日期 |
2004.10.12 |
申请号 |
US20000424951 |
申请日期 |
2000.01.20 |
申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
SRIKANTHA THYAGARAJAN;SOLL DAVID R. |
分类号 |
C12N9/12;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
C12N9/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|