发明名称 |
METHODS AND APPARATA FOR PRECISELY DISPENSING MICROVOLUMES OF FLUIDS |
摘要 |
Devices and methods for depositing fluids on substrates in patterns of spots, lines, or other features use a nozzle, which is preferably configured similarly to a micropipette, having a piezoelectric crystal or other ultrasonic actuator coupled to one of its sides. The nozzle may be charged via capillary action by dipping it into a well containing the fluid to be deposited, and may then be positioned over a desired area of a substrate, at which point activation of the ultrasonic actuator at ultrasonic frequencies will eject the fluid onto the substrate. The needle may subsequently be dipped into a well of rinsing fluid for cleaning. Spots or lines on the order of 5 micrometers width may be generated, making the invention particularly suitable for use in biological applications such as microarray production and in microelectronics applications such as the printing of organic circuitry. |
申请公布号 |
WO2004085064(A2) |
申请公布日期 |
2004.10.07 |
申请号 |
WO2003US28190 |
申请日期 |
2003.09.10 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
LAGALLY, MAX, G.;LAL, AMIT;LEE, CHUNG, HOON;LARSON, BRADLEY, J. |
分类号 |
B01L3/02;B01L99/00;C40B40/06;C40B60/14;G01N35/10 |
主分类号 |
B01L3/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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