发明名称 |
MISMATCH DETECTOR MOLECULE AND MISMATCH DETECTION METHOD, AND USE OF THE SAME |
摘要 |
PROBLEM TO BE SOLVED: To provide a compound at least effectively detecting mismatch of cytosine-cytosine, and a method for detecting mismatch using the same, and a kit to be used for the method and to provide a method detecting abnormality of a base sequence. SOLUTION: A compound expressed by general formula (I) at least forms a pseudo base pair in cytosine-cytosine mismatch. In the formula R<SP>1</SP>and R<SP>2</SP>are each H or 1-5C organic group, and at least one carbon atom in the R<SP>1</SP>may be substituted by N and/or O atom, and R<SP>3</SP>is a 2-20C organic group and at least one carbon atom thereof may be substituted by N, S and/or O atom. Detection of mismatch or existence of mismatch in a base sequence is carried out by detecting formation of the pseudo base pair. COPYRIGHT: (C)2005,JPO&NCIPI
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申请公布号 |
JP2004275179(A) |
申请公布日期 |
2004.10.07 |
申请号 |
JP20030314410 |
申请日期 |
2003.09.05 |
申请人 |
JAPAN SCIENCE & TECHNOLOGY AGENCY |
发明人 |
NAKATANI KAZUHIKO;KOBORI TETSUO;SUDA HITOSHI;SAITO RETSU |
分类号 |
G01N33/53;C12N15/09;C12Q1/68;G01N37/00;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/53 |
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