| 摘要 |
<p>A detector (10, 16) is included as a functional element. Accumulation of mass on, and/or mass transfer through the membrane (3) is influenced by an extracorporeal signal (17) controlling the detector(10, 16). The particle is carried in the blood of humans or animals. The membrane (3) accumulates material (7, 11) from the body itself. Delivery of a pharmaceutical substance (9) through the membrane is dependent on concentration of the material. The membrane (3) is attacked enzymatically in the body. The particle core (2) has a reaction zone for substance conversion. This zone is provided with a bodily intermediate substance (13). The outer diameter of the particle is 50 nm to 10 Microm. Membrane thickness (d) is 2 nm to 1 Microm. The extracorporeal signal (17) is ultrasonic or electromagnetic. The functional element is a fluid lock or channel (5, 5a, 5b). This is functionally- connected with the detector (10, 16). The matrix (4) is a polymer layer. The particle is detected by an image-forming technique. This relies upon the change caused in the particle by mass transfer and/or material accumulation on the membrane. An independent claim is included for the method of detecting the particle.</p> |
