摘要 |
Disclosed are compounds of formula (I), wherein Ar is an aryl or heteroaryl ring selected from the group consisting of phenyl, thiphene, furan, oxazole, thiazole, pyrrole and pyridine, and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of a disorders elected from insulin resistance, glucose intolerance, Type-2 diabetes mellitus, coronary artery disease, elevated blood pressure, hypertension, dyslipidaemia, cancer, menstrual irregularities, hirsutism, infertility, gallbladder disease, restrictive lung disease, sleep apnea, gout, osteoarthritis, and thromboelic disease.
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申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
EBETINO, FRANK HALLOCK;MAZUR, ADAM W;HAYES, JEFFREY CHARLES;WANG, FENG;SOLINSKY, MARK GREGORY;COLSON, ANNY-ODILE;LIN, QISHEN |