发明名称 |
Controlled release by extrusion of solid amorphous dispersions of drugs |
摘要 |
Controlled release dosage forms for low solubility drugs are disclosed wherein an amorphous solid dispersion of the drug is coated with a non-dissolving and non-eroding coating that controls the influx of water to the core so as to cause extrusion of a portion of the core, as well as a method of treating a disease or disorder comprising administering such dosage form to a person.
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申请公布号 |
US2004175428(A1) |
申请公布日期 |
2004.09.09 |
申请号 |
US20040799536 |
申请日期 |
2004.03.11 |
申请人 |
PFIZER INC. |
发明人 |
APPEL LEAH E.;CURATOLO WILLIAM J.;HERBIG SCOTT M.;NIGHTINGALE JAMES A.S.;THOMBRE AVINASH G. |
分类号 |
A61K9/00;A61K9/14;A61K9/16;A61K9/26;A61K9/36;A61K9/50;(IPC1-7):A61K9/24 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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