DYRKS AS MODIFIERS OF THE APC AND AXIN PATHWAYS AND METHODS OF USE
摘要
Human DYRK genes are identified as modulators of the APC and Axin pathways, and thus are therapeutic targets for disorders associated with defective APC and Axin function. Methods for identifying modulators of APC and Axin, comprising screening for agents that modulate the activity of DYRK are provided.
申请公布号
WO2004072257(A2)
申请公布日期
2004.08.26
申请号
WO2004US03803
申请日期
2004.02.10
申请人
EXELIXIS, INC.;GENDREAU, STEVEN, BRIAN;MORABLANCO, EVA, LORENA;HEUER, TIMOTHY, S.;LICKTEIG, KIM
发明人
GENDREAU, STEVEN, BRIAN;MORABLANCO, EVA, LORENA;HEUER, TIMOTHY, S.;LICKTEIG, KIM
