发明名称 |
CHARACTERIZATION AND ISOLATION OF SUBSETS OF HUMAN EMBRYONIC STEM CELLS (HES) AND CELLS ASSOCIATED OR DERIVED THEREFROM |
摘要 |
A sub-population of HES cells is identified which is positive for specific HES markers. These cell types are identified by expression of particular GCTM-2 antigens. A method based on the identification of GCTM-2 can differentiate between substantially undifferentiated or differentiated cell populations. Spontaneous differentiation often occurs in HES cultures resulting in non-homogeneous cell cultures. The invention also provides further sub populations of cells within differentiated cultures of HES cells that are SCL or epithelial in nature. |
申请公布号 |
EP1448763(A1) |
申请公布日期 |
2004.08.25 |
申请号 |
EP20020774172 |
申请日期 |
2002.11.11 |
申请人 |
ES CELL INTERNATIONAL PTE LTD. |
发明人 |
PERA, MARTIN, FREDERICK;LASLETT, ANDREW;HAWES, SUSAN;GION, TOMONOBU |
分类号 |
A61K35/12;C12N5/0735;C12N5/074;(IPC1-7):C12N5/06;C12N5/08 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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