发明名称 |
Atorvastatin hemi-calcium Form VII. |
摘要 |
The present invention provides a novel form of atorvastatin hemi-calcium designated Form VII and novel processes for its preparation whereby another crystalline form of atorvastatin hemi-calcium is suspended in ethanol, preferably absolute ethanol, and is converted to the new form, which is then isolated. The present invention further provides a method of reducing the plasma low density lipoprotein level in patients suffering from or susceptible to hypercholesterolemia and compositions and dosage forms for practicing the invention. |
申请公布号 |
ZA200303972(B) |
申请公布日期 |
2004.08.23 |
申请号 |
ZA20030003972 |
申请日期 |
2003.05.22 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
JUDITH ARONHIME;RAMI LIDOR-HADAS;VALERIE NIDDAM-HILDESHEIM;REVITAL LIFSHITZ-LIRON |
分类号 |
A61K31/40;A61P1/06;A61P3/06;A61P9/10;A61P43/00;C07D207/34;C07D405/06 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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