发明名称 |
ENDOBRONCHIAL DELIVERY OF ANTIBIOTIC IN INDIVIDUALS WITH IMPAIRED LUNG TISSUE OR LUNG FUNCTION |
摘要 |
Methods for producing a significant anti-P. aeruginosa effect in a cystic fibrosis patient 6 years of age or younger that presents with early P. aeruginosa infection are disclosed. Such methods involve endobronchial administration of an aerosolized tobramycin formulation, wherein said formulation is administered as a monotherapy for a period of about one month. In addition, methods for selecting a cystic fibrosis patient 6 years of age or younger that my benefit from the claimed methods, as well as methods for monitoring anti- P. aeruginosa aerosol antibiotic treatment outcome in such patients, are disclosed. |
申请公布号 |
WO03101390(A3) |
申请公布日期 |
2004.08.12 |
申请号 |
WO2003US17151 |
申请日期 |
2003.05.30 |
申请人 |
CHILDRENS HOSPITAL AND REGIONAL MEDICAL CENTER;RAMSEY, BONNIE;GIBSON, RONALD |
发明人 |
RAMSEY, BONNIE;GIBSON, RONALD |
分类号 |
A61K31/7036 |
主分类号 |
A61K31/7036 |
代理机构 |
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代理人 |
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地址 |
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