| 摘要 |
Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12. and R13 are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolic dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount. |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;KARO BIO AB;WASHBURN, WILLIAM, N.;MENG, WEI;RYONO, DENIS, E.;ELLSWORTH, BRUCE, A.;ERICSSON, THOMAS;RAHIMI- GHADIM, MAHMOUD;GARG, NEERAJ;MALM, JOHAN |
发明人 |
WASHBURN, WILLIAM, N.;MENG, WEI;RYONO, DENIS, E.;ELLSWORTH, BRUCE, A.;ERICSSON, THOMAS;RAHIMI- GHADIM, MAHMOUD;GARG, NEERAJ;MALM, JOHAN |
