发明名称 4-(Phenyl-(piperidin-4-yl)-amino)-benzamide derivaties and their use for the treatment of pain, anxiety or gastrointestinal disorders
摘要 Compounds of general formula (1): R<1 >is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl, pyrrolyl, triazolyl, thiazolyl and pyridine N-oxide; where each R<1 >phenyl ring and R<1 >heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain, anxiety and functional gastrointestinal disorders.
申请公布号 US2004152731(A1) 申请公布日期 2004.08.05
申请号 US20030477853 申请日期 2003.11.13
申请人 BROWN WILLIAM;GRIFFIN ANDREW;WALPOLE CHRISTOPHER 发明人 BROWN WILLIAM;GRIFFIN ANDREW;WALPOLE CHRISTOPHER
分类号 C07D211/58;A61K31/4468;A61K31/4523;A61K31/4525;A61K31/4535;A61K31/454;A61K31/4545;A61P1/04;A61P1/12;A61P1/14;A61P9/10;A61P9/12;A61P11/00;A61P13/02;A61P19/08;A61P23/00;A61P25/02;A61P25/04;A61P25/16;A61P25/18;A61P25/22;A61P25/30;A61P25/32;A61P25/34;A61P25/36;A61P29/00;C07D401/06;C07D405/06;C07D407/06;C07D409/06;C07D417/06;(IPC1-7):A61K31/454;A61K31/453;C0749/02;C0741/02;A61K31/445 主分类号 C07D211/58
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