| 摘要 |
A pharmaceutical or veterinary paste formulation, which, based upon total weight of composition, comprises: (a) about 0.01 to about 50% of a therapeutic agent; (b) about 0.02 to about 20% fumed silica; (c) about 0.01% to about 20% of a viscosity modifier selected from the group consisting of PEG 200, PEG 300, PEG 400, PEG 600, monoethanolamine, diethanolamine, triethanolamine, glycerol, propylene glycol, polyoxyethylene sorbitan monoolerate, block copolymer mixtures of polyoxyalkylene compounds, nonylphenol ethoxylates, polyethylene glycols, linear alcohol ethoxylates, polyethylene glycol paraisooctyphenyl ethers, and propylene glycol mono- and di-fatty acid esters; (d) 0% to about 30% of an absorbent; (e) 0% to about 20% of a colorant; and (f) a carrier selected from the group consisting of triacetin, short to medium chain mono-, di-, or tri-glycerides, glycerin, water, propylene glycol, N-methyl pyrrolidinone, glycerol formal, polyethylene glycol, polyethylene glycol-polypropylene glycol-polyethylene glycol tri-block copolymers, transcutol, benzyl alcohol, N, N-dimethylformamide, and dimethylsulfoxide.
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